Blood Pressure Components and Changes in Relation to White Matter Lesions

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Blood pressure components and changes in relation to white matter lesions: a 32-year prospective population study.

This study aimed to examine the long-term effect of high blood pressure (systolic blood pressure, diastolic blood pressure, pulse pressure, and mean arterial pressure) on white matter lesions and to study changes in different blood pressure components in relation to white matter lesions. A representative population of women was examined in 1968 and re-examined in 1974, 1980, 1992, and 2000. The...

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Extent of cerebral white matter lesions is related to changes of circadian blood pressure rhythmicity.

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High prevalence of white matter hyperintensities in normal aging: relation to blood pressure and cognition.

The occurrence of cerebral white matter hyperintensities (WMHs), and their associations with blood pressure, episodic memory, and other cognitive tasks, were examined in a population-based sample of 123 individuals between 64 and 74 years old. Magnetic Resonance Imaging (MRI) detected subcortical and periventricular hyperintensities in 90% and 67% of the cases, respectively. Subcortical WMHs we...

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Blood Pressure Control in Aging Predicts Cerebral Atrophy Related to Small-Vessel White Matter Lesions

Cerebral small-vessel damage manifests as white matter hyperintensities and cerebral atrophy on brain MRI and is associated with aging, cognitive decline and dementia. We sought to examine the interrelationship of these imaging biomarkers and the influence of hypertension in older individuals. We used a multivariate spatial covariance neuroimaging technique to localize the effects of white matt...

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Longitudinal Changes of White Matter Lesions

INTRODUCTION: Quantification of white matter lesion progression is of major interest in MR imaging of the human brain for the diagnosis and monitoring of several diseases like Multiple Sclerosis or Alzheimer’s disease. T1 (T1w) and T2 (T2w) weighted images may provide insufficient tissue contrast for accurate segmentation of lesions. The Fluid Attenuated Inversion Recovery (FLAIR) sequence is o...

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ژورنال

عنوان ژورنال: Hypertension

سال: 2009

ISSN: 0194-911X,1524-4563

DOI: 10.1161/hypertensionaha.109.129700